ABSTRACT
Justification. Diagnostics, surgical tactics, postoperative treatment of spontaneous retroperitoneal hematoma (SRH) are still a complex section in medicine. The mortality rate of SRH is high and amounts to about 20%. Scientific interest to the problem of SRH has arisen with the rapid worldwide spread of COVID-19 since the end of 2019. Due to the widespread use of anticoag-ulants and the development of COVID-19-associated coagulopathy, the incidence of retroperitoneal hematomas in patients with COVID-19 is higher than in the general population. Materials and methods. Throughout the year more than 16806 COVID-19patients were assisted. Of these, SRH developed in 5 patients. Results. SRH was found posthumously in 2 patients. Emergency surgery — lumbotomy with revision of the retroperitoneum — was performed in three patients. Conclusions. Low molecular weight heparin and other members of the anticoagulant group can cause severe hemorrhagic com-plications in COVID-19 patients. © 2021, Media Sphera Publishing Group. All rights reserved.